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Swine Flu, Shmine Flu

The swine flu is here! Run for the hills! The global freak-out over the H1N1 virus has been a major news story, of late, but gamers are no strangers to global pandemics and strange diseases. Over the years, gamers have been treated to any number of virtual pandemics, ranging from mutagenic zombie plagues to targeted bio-weapons. Join us on a journey through the fictional outbreak hall of fame.

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Dysentery

Your virtual settlers could fall prey to any number of ailments, attacks and pitfalls, but perhaps the worst was dysentery, the digestive disease that was, it seemed, inevitable on that long journey west.
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Forced Evolutionary Virus

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Creeping Derangea

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Chimera Virus

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Venom Symbiote

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Porphyric Hemophilia

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FoxDie

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Corrupted Blood

Was it a glitch? Or was it a fascinating study of the way real-word epidemics can spread?
At any rate, Blizzard was eventually forced to reset all the game's servers to kill the Corrupted Blood bug.
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T-Virus