ScienceDaily (May 14, 2008) — A team of Canadian researchers has completed a massive survey of the network of protein complexes that orchestrate the fundamental processes of life. In the online edition of the journal Science, researchers from the Université de Montréal describe protein complexes and networks of complexes never before observed -- including two implicated in the normal mechanisms by which cells divide and proliferate and another that controls recycling of the molecular building blocks of life called autophagy.

These processes are implicated in diseases such as cancers and autophagy has recently been shown to be involved in degenerative neurological disorders such as Alzheimer's and Huntington's diseases. The discovery will fill gaps in basic knowledge about the workings and evolutionary origins of the living cell and provide new avenues to explore in linking these fundamental processes to human disease.