Can religion and spirituality be considered purely as "neural blips and fluxes in brain chemistry"? Using recent advances in brain imaging and neuropsychological research, co-authors Dr. Andrew Newberg and the late Dr. Eugene D'Aquili, both of the University of Pennsylvania, explore that question and arrive at some surprising conclusions about material and spiritual "reality." This article, adapted for Science & Spirit magazine from their 1999 book The Mystical Mind: Probing the Biology of Religious Experiences, presents an overview of some of their findings.